It affects patients who drink little to no alcohol. MASLD may not cause symptoms. Nonalcoholic fatty liver disease (NAFLD) is the buildup of fat in the liver that is not caused by drinking too much alcohol. NAFLD is usually but not always related to being overweight. Non-alcoholic fatty liver disease (NAFLD) is caused by a buildup of fat in the liver and is the most common form of liver disease in the United States. . Dec 12, 2025 ยท Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly called nonalcoholic fatty liver disease (NAFLD), is a liver condition that affects people with excess weight, obesity or other metabolic conditions, such as type 2 diabetes, high blood pressure or high cholesterol. Nonalcoholic fatty liver disease, or NAFLD (also referred to as metabolic dysfunction-associated steatotic liver disease, or MASLD), is a condition in which excess fat builds up in your liver. Metabolic dysfunction-associated steatotic liver disease (MASLD) used to be called nonalcoholic fatty liver disease. This buildup of fat is not caused by heavy alcohol use.

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